Hypokalemia: Clinical: Video, Causes, & Meaning | Osmosis
Hypokalemia: Clinical: Video, Causes, & Meaning | Osmosis
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Hypokalemia: Video, Causes, & Meaning | Osmosis
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Hypokalemia: Video, Causes, & Meaning | Osmosis
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Hypokalemia - Symptoms, Causes, Treatment | NORD
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Why long-term Omeprazole can cause hypomagnesemia Omeprazole (a PPI) reduces stomach acid. With prolonged use, this impairs intestinal magnesium absorption by affecting magnesium transport channels (TRPM6/7). Over time, this leads to low serum magnesium levels. Why it matters: Hypomagnesemia can cause: •Muscle cramps & weakness Seizures •Cardiac arrhythmias •Secondary hypocalcemia & hypokalemia Clinical pearl: Magnesium levels often normalize only after stopping the PPI, not just with supplement
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Why long-term Omeprazole can cause hypomagnesemia Omepraz…
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📌Clinical Guide: Torsades de Pointes (TdP) & Long QT Syndrome (LQTS) --- Key Causes 1. Drug-Induced QTc Prolongation: - High-risk agents: Amiodarone, fluoroquinolones, macrolides, SSRIs, antipsychotics, antiemetics. 2. Electrolyte Imbalances: Hypokalemia, hypomagnesemia. 3. Inherited LQTS: LQTS1/2/3 mutations (confirm via genetic testing). Diagnosis - ECG: QTc ≥460 ms (women) / ≥450 ms (men). - Indeterminate Cases: Holter monitor, exercise stress testing. Acute TdP Management 1. Immediate Actio
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