Which problems are the biggest, most tractable, and most neglected in the world - and what can you do about them?

What are the biggest problems and issues in the world that are the most important to solve? Here's what we learned after 10 years of research.

Jun 18, 2025 · So we’ve now decided to focus the list on object-level problems and discuss broader approaches to working on these problems elsewhere. This change does not mean we think ‘meta’ …

This is one of many profiles we've written to help people find the most pressing problems they can solve with their careers. Learn more about how we compare different problems and see how this problem …

Oct 8, 2024 · To help our readers think this through, we publish a list of what we see as the world’s most pressing problems. We rank the top most issues by our assessment of where additional work and …

After making the argument that the existential risk from power-seeking AI is a pressing world problem, we’ll discuss objections to this argument, and how you can work on it. (There are also other major …

Focusing on specific world problems or threats: This approach involves addressing specific issues such as the risk of Iran acquiring a nuclear weapon, mitigating climate change, or bioweapon threat …

Want to learn more about global issues we think are especially pressing? See our list of issues that are large in scale, solvable, and neglected, according to our research.

What are the major arguments against improving decision making being a pressing issue? It’s unclear what the best interventions are — and some are not very neglected. As we covered above, we’re not …

To find impactful organisations, think about which problems you think are most pressing, and then try to identify the best organisations addressing those problems. (In our problem profiles, we list …