Anaphase in budding yeast is triggered by cleavage of the central subunit, Scc1, of the chromosomal cohesin complex by the protease separase. Here we show that separase also cleaves the ...
The anaphase-promoting complex/cyclosome (APC/C) is an ubiquitin ligase that functions during mitosis. Here we identify the transcriptional regulator, transcriptional intermediary factor 1γ, TIF1γ, as ...
Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to ...
Team discovers transient rise in depletion attraction contributes to mitotic chromosome condensation
(A) Histone staining images and OI-DIC density imaging of human living cells in the interphase (the phase between cell divisions, left) and mitotic phase (right). The bottom two rows are OI-DIC ...
The process of mitosis has made more clear, thanks to recent research. A new study describes how Topo 2, an enzyme that disentangles DNA molecules and is essential for proper cell division. At this ...
Cell biology professor [Mike] has created a way for blind students to decipher microscope slides using 3D prints and the magic of capacitive sensing. His write-up focuses on a slide showing the ...
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